Published November, 2010
By Sukriti Nag
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Opening with components of the neurovascular unit and the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, this book reviews imaging techniques, molecular study methods, and techniques for delivering therapeutic agents across the BBB.

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Published November, 2010
By Ashok Mulchandani, Kim R. Rogers and Kim Rogers
Publisher: Springer (Humana Press Inc.)
Series: Methods in Biotechnology
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Availability: Available

The purpose of the two volumes of Protocols and Te- niques in Biosensors is to provide a basic reference tool and starting point for use by graduate students, postdoctoral and senior researchers, and technicians m academics, industry, and government research establishments, to enable rapid entry into the field of biosensors.

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Published November, 2010
By Federico Innocenti
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with HaploChIP, SNP genotyping in DNA pools, and PharmGKB, the pharmacogenetics and pharmacogenomics knowledge base.

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Published November, 2010
By Mark P. Mattson
Publisher: Springer (Humana Press Inc.)
Series: Contemporary Neuroscience
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Availability: Available

As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative disorders as Alzheimer's, Parkinson's, and Huntington's diseases.

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Published November, 2010
By Mark Giezen and Mark van der Giezen
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

In this updated volume, experts from around the world provide the latest protocols for isolating different organelles and the localization of particular proteins using a variety of methods such as light, confocal, and electron microscopy. Emphasis is placed on protein targeting of cellular compartments in both prokaryotic and eukaryotic systems.

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Published November, 2010
By Beverly A. Teicher
Publisher: Springer (Humana Press Inc.)
Series: Cancer Drug Discovery and Development
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Availability: Available

Thus, as some new therapeutic targets have been defined and new therapeutic strategies have been attempted, so have some new biological hurdles resulting from tumor evasion of the intended therapeutic attack been discovered.

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Published November, 2010
By Keith E. Herold, Avraham Rasooly and Keith Herold
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

Biosensors combine biological recognition elements and signal conversion elements into a biodetection system. This book describes the major technologies in the field in extensive technical detail, providing a user-friendly guide to this vital technology.

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Published November, 2010
By Qing Yan
Publisher: Springer (Humana Press Inc.)
Series: Methods in Molecular Biology
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Availability: Available

The volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases.

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Published November, 2010
By Luciano Cerulli and Carlo Cavallotti
Publisher: Springer (Humana Press Inc.)
Series: Aging Medicine
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Availability: Available

Aging research on the human eyes crosses all areas of ophthalmology and also relies upon biological, morphological, physiological, and biochemical tools for its study. In addition to descriptions of age-related changes in almost all the structures of the human eyes, the authors also include interesting accounts of personal experiments and data.

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Published November, 2010
By Phil Skolnick
Publisher: Springer (Humana Press Inc.)
Series: Contemporary Neuroscience
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Availability: Available

In this book, leading-edge investigators offer effective strategies to improve current antidepressive therapies and suggest molecular, biological, and genetic approaches that will lead to the development of novel antidepressants.

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