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Main description:
This volume contains those papers which were presented at the Second International Symposium on Oxygen Transport to Tissue, to- gether with the discussions which followed. These discussions were generously summarized by the chairmen of the various sessions. This symposium in Mainz was the third international meeting, after those held in Dortmund in 1971 and Charleston-Clemson in 1973, which dealt primarily with problems relating to oxygen transport to tissue under physiological and pathophysiological conditions. It was the second symposium conducted by the International Society on Oxygen Transport to Tissue which was founded in 1973. We dedicate this volume to the memory of the first president of the International Society on Oxygen Transport to Tissue, Dr. Mel- vin H. Knisely. July, 1975 JUrgen Grote Daniel D. Reneau Gerhard Thews Contents Welcome xxi G. Thews Session I - OXYGEN MEASUREMENTS IN BLOOD AND TISSUE A Method for Simultaneous Measurements of Bioelectric Activity and Local Tissue P02 in the CNS * * . * ...* * . * 3 A. Lehmenkuhler, H. Caspers, and E. -J. Speckmann Oxygen Fields Induced by Recessed and Needle Oxygen Microelectrodes in Ho- geneous Media * . * . * 9 G.
Schneiderman and T. K. Goldstick The Application of Histological Analysis for the Localization of Tissue P02 and Local Blood Flow with the Example of the Glomus Caroticum of the Rabbit (Oryctolagus cuniculus) . . * * ...* * * . . * . * . . * . 17 H. Weigelt, E. Seidl, H. Acker, and D. W.
Contents:
Session I - Oxygen Measurements in Blood and Tissue.- A Method for Simultaneous Measurements of Bioelectric Activity and Local Tissue PO2 in the CNS.- Oxygen Fields Induced by Recessed and Needle Oxygen Microelectrodes in Homogeneous Media.- The Application of Histological Analysis for the Localization of Tissue PO2 and Local Blood Flow with the Example of the Glomus Caroticum of the Rabbit (Oryctolagus cuniculus).- A Method for Measuring Oxygen Uptake Rate Distributions Over the Surface Zone of Excised Tissues Using a 91-Cathode Electrode.- Monitoring of PO2 in Human Blood.- A New Approach to the Experimental Measurement of Mean Tissue PO2.- Pyrene Butyric Acid: A Non-Invasive Probe for In Situ Intracellular Oxygen Concentration.- Kryomicrophotometry as a Method for Analyzing the Intracapillary HbO2 Saturation of Organs Under Different O2 Supply Conditions.- Quantitative Fluorescence Photometry with Biological Fluids and Gases.- Control of Electrode Aging by a Periodic Anodization Technique.- Session II - Blood Oxygenation.- Effects of 2,3-Diphosphoglycerate on Functional Properties of Hemoglobin and on Glycolysis of Human Erythrocytes.- The Effect of Red Cell 2,3-DPG Changes Induced by Diabetic Ketoacidosis on Parameters of the Oxygen Dissociation Curve in Man.- The Influence of MgCl2 on the O2-Hb-Binding Curve of Human Hemoglobin Under Intracellular Conditions.- Oxygen Transport and Hemodynamics of Stroma-Free Hemoglobin Solutions.- Oxygen Transport on Mount Everest: The Effects of Increased Hematocrit on Maximal O2 Transport.- Measurement of Oxygenation and Deoxygenation of a Single Red Cell of Chicken Embryo by Means of a Microphotometer.- Session III - Tissue Respiration.- Cellular Control of Mitochondrial Respiration.- Influence of Hemoglobin Oxygen Affinity on Oxidation Reduction State of Cytochrome aa3 in Perfused Liver.- Problems in Determination of Oxygen Dissociation of Avian Blood.- Metabolic and Electron Microscopic Studies Post Mortem in Brain Mitochondria.- Early Structural Changes in Mitochondria in Response to Acute Reductions in Capillary Flow.- The Induction of Cytochrome P-450 by Hypoxia.- Session IV - Oxygen Diffusion in Blood and Tissue.- Diffusion of Oxygen in Plasma and Blood.- Facilitated Diffusion of Oxygen in Red Blood Cell Suspensions.- Measurement of Diffusivity and Metabolic Rate of O2 and CO2 in Respiring Tissue.- Facilitated Diffusion of CO and Oxygen in the Presence of Hemoglobin or Myoglobin.- The Measurement of the Fraction of Oxygen Carried by Facilitated Diffusion.- Measurement of Diffusion Parameters with Noble Metal Electrodes.- Session V - Mathematical Models to Describe Oxygen Transport in Blood and Tissue.- A Generalized Advancing Front Model Describing the Oxygen Transfer in Flowing Blood.- A Theoretical Model of the Respiratory Function of Blood.- Some Model Results on Hemoglobin Kinetics and Its Relationship to Oxygen Transport in Blood.- The Mechanical Basis for Fick's Law and Its Generalizations.- A Stochastic Model for the Transport of Oxygen to Brain Tissue.- Models for O2 and CO2 Transfer in Macroscopic Flow Channels and Their Physiological Implications.- Session VI - Oxygen Supply of the Central Nervous System.- Correlation Between the Redox State, Electrical Activity and Blood Flow in Cat Brain Cortex During Hemorrhagic Shock.- Cortical NADH, pO2, Electrical Activity and Arterial Blood Pressure Oscillations in Hypoxaemia.- The Effect of Decapitation on the Oxidation-Reduction State of NADH and ECoG in the Brain of the Awake Rat.- Cerebral Oxygen Supply in Brain Edema and During Ventriculo-Cisternal Perfusion.- Tissue Responses to Hypoxia, Shock and Stroke.- Cerebral Oxygenation in Arterial Hypoxia.- Theoretical and Experimental Aspects of Brain Tissue Oxygenation Dynamics.- Session VII - Oxygen Supply of the Central Nervous System.- Local Tissue PO2 and Microflow of the Brain Cortex Under Varying Arterial Oxygen Pressure.- An Analysis of Ion Distribution in Brain Following Anoxia.- Comparison of Oxygen Tension in the Spinal Cord and Globus Pallidus During Hyperbaric Oxygen Exposure of Rats Under Pentobarbital Anesthesia.- Autonomic and Pharmacological Control of Oxygen Autoregulation Mechanisms in Brain Tissue.- Effects of So-Called "Cerebral Blood Flow Increasing" Drugs on Tissue-Oxygenation of the Brain.- Session VIII - Oxygen Supply of Different Organs.- Oxygen Supply to the Open Rabbit Cornea.- Studies on Retinal Oxygenation.- A System for In Vivo Measurement of Oxygen in Intraocular Tissue.- The O2 Supply of the Isolated Cell-Free Perfused Rat Kidney.- Effect of Vasopressors and Hemorrhage on Intrarenal Oxygenation.- Renal Tissue Oxygenation During Hypoxic Hypoxia.- Corneal Oxygen Supply Conditions.- Session IX - Common Aspects of Oxygen Supply.- Cellular Oxygen Concentration.- The Role of Carotid Chemoreceptors in the Regulation of Arterial Oxygen Transport under Hypoxia with and without Hypercapnia.- Pulmonary Tissue Oxygen Requirement.- Oxygen Delivery and Utilization in Hypoxic Dogs Made Acidemic and Alkalemic.- Evidence Against Local Control of Intestinal Tissue Oxygenation by Myogenic Mechanisms.- Effect of Ionizing Radiation on Liver Microcirculation and Oxygenation.- A Factor in Longitudinal Tissue Gradients: Red Cell Carriage.- Effects of Dopamine and Epinephrine on Intestinal Blood Flow and Oxygen Uptake.- Session X - Respiratory Gas Exchange and Metabolism in Tumor Tissue.- In Vivo Utilization of Oxygen and Glucose by Neoplastic Tissue.- O2 Supply Conditions in Tumor Tissue In Vivo.- Pathophysiological Aspects of Glucose Uptake by the Tumor Tissue Under Various Conditions of Oxygen and Glucose Supply.- Solution of the Diffusion Field Equation of Substrate Concentration in the Intercapillary Region Considering the Decrease in Substrate Consumption in the Unsaturated Region of Cancer Cell Glycolysis and Respiration.- Computation of Glucose and O2 Concentration Distribution in the Intercapillary Region of Intact Tumor Tissue Considering the Decrease in Substrate Consumption in the Unsaturated Region of Cancer Cell Glycolysis and Respiration.- Mesenchyme Theory on the Increase in Resistance Experienced During Repetition of Cancer Therapy Processes.- Session XI - Respiratory Gas Exchange and Metabolism in Tumor Tissue.- Studies on the Ability of the Tumor Respiration In Vivo to Fulfill Its Physiological Functions.- Control Mechanisms of Oxygen and Glucose Utilization in Tumours.- Oxygen Distribution in Tumours: Influence on Cell Proliferation and Implications for Tumour Therapy.- Preliminary Observations of Oxygen Levels in Microcirculation of Tumors in C3H Mice.- The Distribution of Oxygen Consumption Rates in Some Tissues Before and after X-Irradiation.- Session XII - Oxygen Supply of Muscle Tissue.- Mechanisms of Circulation Metabolism Coupling in Skeletal Muscle.- Spontaneous Oscillations of PO2 in Muscle Tissue.- Tissue PO2, VO2, Venous PO2 and Perfusion Pressure in Resting Dog Gracilis Muscle Perfused at Constant Flow.- Effect of a Shift of the Oxygen Dissociation Curve on Myocardial Oxygenation at Hypoxia.- Tissue Blood Flow and Oxygenation During Large Vessel Surgery.- Mechanisms of Increased Tissue Oxygen Delivery Following Release of Arterial Occlusion in Canine Skeletal Muscle and Skin.- Mean Myoglobin Oxygen Tension During Exercise at Maximal Oxygen Uptake.- Oxygen Transport in Skeletal Muscle: Capillary Geometry in Longitudinal Section.- The Measurement of Myocardial Microflow and Its Reaction to Hypoxia and Hypercapnia.- Session XIII - Perinatal Oxygen Supply.- Oxygen Uptake of the Guinea Pig at Decreased and Increased Maternal Placental Blood Flow.- Development and Adaptation of Heart Mitochondrial Respiratory Chain Function in Fetus and in Newborn.- Experimental and Theoretical Analysis of Oxygen Transport in Fetal Brain.- Fetal and Placental O2 Consumption and the Uptake of Different Metabolites in the Ruminant and Horse During Late Gestation.- Continuous PO2 and Heart Rate Recording in the Human Newborn.- A Comparison of Transcutaneous and Arterial PO2 in Sick Neonates.- Effect of Umbilical Artery Catheters on Oxygen Supply to Extremities.- Tissue Oxygen Available (O2a) as a Criterion for the Effectiveness of Continuous Positive Pressure Breathing (CPPB).- Contributors.
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Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: December, 2012
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Weight: 1510g
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Subcategories: Haematology
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Richard Wilson
Yongwon Choi
Robert D. Perry
Gáspár Jékely
Dihua Yu
John D. Lambris
Duane F. Bruley
Michael R. Shurin
Fabrizio d'Adda di Fagagna
Gerard Pasterkamp
Bharat B. Aggarwal
Vicente Felipo
Setsuro Ebashi
Stephen P. Schoenberger
Simone Mocellin
Peter D Wagner
John P. Fisher
Stanley Perlman
Jean-Pierre Saint-Jeannet
Simo S. Oja
Duane F. Bruley
John D. Lambris
Constantine Tsoukas
Nagy A. Habib
Uwe Lendeckel
Constancio Gonzalez
Joseph T. Coyle
Richard Blumberg
Nasimul Ahsan
Marelyn Wintour-Coghlan
Joe G. Hollyfield
















































































































































































































































































































































































































































































































































































































































































































































































































































































































































