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Genome Profiling for Genetic Marker Discovery
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Main description:

Recent advancement in genome technology, especially high throughput low cost sequencing and microarrays, revolutionizes the way for discovering genetic markers and enables their new applications. This volume is designed to build a genetic tool box with these emerging techniques for molecular biologists, geneticists, clinical scientists and breeders. While theses methods and protocols were developed in genomics and bioinformatics laboratories in the forefront of the fields, the format of each method or protocol is easy to understand and practical to address different challenging issues in genetic marker discovery.


Contents:


Preface



Part I. Microarray-assisted DNA marker discovery (6)



Genetic discovery by genomics



GeneChip microarray for expression and genetic analysis


Gene Tanimoto, Affymetrix Inc.



Sample preparation for genome profiling


Charles Chilcott and Tong Zhu, Syngenta Biotechnology, Inc., Research Triangle Park, NC 27709



SFP detection from genome profiles


Justin Borevitz, University of Chicago, Department of Ecology and Evolution, Chicago, IL 60637, USA



Single feature polymorphism detection in rice


Henry Nguyen, Division of Plant Sciences, University of Missouri-Columbia, Columbia, Missouri, USA



Genome resequencing by GeneChip microarrays



High resolution SFP detection by tiling arrays


David Gresham, Lewis-Sigler Institute for Integrative Genomics and Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA



Part II. High density marker applications (5)



ExTreme array mapping of quantitative trait loci


David J. Wolyn, Department of Plant Agriculture, University of Guelph, Guelph, Ontario N1G 2W1, Canada



Ultra-high density mapping by genome profiling


Christopher Basten, Syngenta Biotechnology, Inc., Research Triangle Park, NC 27709, USA



Microarray assisted positional gene cloning


Ji-Ming Gong and Julian I. Schroeder, Division of Biological Sciences, Cell and Developmental Biology Section and Center for Molecular Genetics, University of California at San Diego, La Jolla, CA 92093, USA



Elucidating genetic diversity with oligonucleotide arrays


Elizabeth Winzeler, Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA



Single-feature polymorphism data for inference in population genetics


Simon Tavaré Molecular and Computational Biology Program, University of Southern California, CA 90089, USA



Part III. Combine genetic and functional information (9)



SFP detection from complex transcriptome


Robbie Waugh, Scottish Crop Research Institute, Genome Dynamics, Invergowrie, Dundee, DD2 5DA, Scotland, UK



Detection and applications of gene expression markers


Marilyn West and Richard Michelmore, Department of Plant Sciences and The Genome Center, University of California–Davis, Davis, CA 95616, USA



Detecting single-feature polymorphisms by robustified projection pursuit


Xinping Cui, Department of Statistics, University of California Riverside, CA 92521, USA



Statistical analysis for SFP identification from RNA data


Weibo Xie and Qifa Zhang, Huazhong Agricultural University, Wuhan, China



Microarray experimental design strategies for genetical genomics studies


Guilherme J. M. Rosa, Department of Animal Science and Department of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan 48824



Statistical methods for expression quantitative trait loci (eQTL) mapping


C. M. Kendziorski, Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin 53703, USA



A Bayesian clustering method for analysis of all expressed transcripts and markers jointly in a single model


Shizhong Xu, Department of Botany and Plant Sciences, University of California, Riverside, California 92521, USA



eQTL Viewer: visualizing how sequence variation affects genome-wide transcription


Zhao-Bang Zeng, Bioinformatics Research Center, Department of Statistics, and Department of Genetics, North Carolina State University, Raleigh, NC 27695, USA



e-QTL case study: Dissect genetic regulation of gene expression in Arabidopsis shoot development


Stephen Howell, Plant Sciences Institute, Iowa State University, Ames, IA 50011, USA



Part IV. Beyond model systems (4)



Rapid and cost-effective polymorphism identification using restriction site associated DNA (RAD) markers


Eric Johnson, Institute for Molecular Biology, University of Oregon, Eugene, Oregon 97403

Diversity Arrays Technology (DArT) for whole-genome profiling


Andrzej Kilian, Center for the Application of Molecular Biology to International Agriculture and Diversity Arrays Technology Pty. Ltd., Canberra, ACT 2601, Australia

Whole genome SNP discovery by pyrosequencing


Donald R McCarty, Horticultural Sciences Department, University of Florida, Gainesville, FL 32611, USA



Complexity Reduction of Polymorphic Sequences (CRoPS) technology for SNP marker discovery


Michiel J.T. van Eijk, Keygene N.V., Agro Business Park 90, 6700 AE Wageningen, The Netherlands


PRODUCT DETAILS

ISBN-13: 9781603273503
Publisher: Springer (Humana Press)
Publication date: December, 2013
Pages: 300
Weight: 652g
Availability: Not available (reason unspecified)
Subcategories: General Issues, Genetics
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