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MORE ABOUT THIS BOOK
Main description:
This volume details methods and protocols for the synthesis and characterization of glycopolymers and their biomedical applications. Chapters are divided into three parts covering synthesis and characterization of glycopolymers; glycopolymer-nanoparticle conjugates; and surface immobilized glycopolymers. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Macro-Glycoligands: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Contents:
Part I: Synthesis and Characterization of Glycopolymers
1. Synthesis of Chain-end Functionalized Glycopolymers via Cyanoxyl Mediated Free Radical Polymerization (CMFRP)
Valentinas Gruzdys, Jinshan Tang, Elliot Chaikof, Xue-Long Sun
2. Protecting-group-free Synthesis of Well-defined Glycopolymers Featuring Negatively Charged Oligosaccharides
Luca Albertin
3. Glycopolymers Prepared by Ring-opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole Forming 'Click' Reaction
Ronald Okoth and Amit Basu
4. Protecting-group-free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza Virus
Tomonari Tanaka, Tadanobu Takahashi, and Takashi Suzuki
5. Carbohydrate-based Initiators for the Cationic Ring-opening Polymerization of 2-Ethyl-2-oxazoline
Christine Weber,Michael Gottschaldt, Richard Hoogenboom, Ulrich S. Schubert
6. Heterofunctional Glycopolypeptides by Combination of Thiol-ene Chemistry and NCA Polymerization
Kai-Steffen Krannig and Helmut Schlaad
7. Preparation of Proteoglycan Mimetic Graft Copolymers
Matt J. Kipper and Laura W. Place
Part II: Glycopolymer Nanoparticle Conjugates
8. Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug Nanocarriers
Mona Semsarilar, Irene Canton, and Vincent Ladmiral
9. Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications
Christian K. Adokoh, James Darkwa, and Ravin Narain
10. Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer using Thiol-Halogen Click Chemistry
Wentao Song and Anthony M. Granville
11. Glycopolymer-grafted Polymer Particles for Lectin Recognition
Michinari Kohri, Tatsuo Taniguchi, and Keiki Kishikawa
12. Synthesis of Non-spherical Glycopolymer-decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry
Xiao Li, Weidong Zhang,and Gaojian Chen
13. Synthetic Approach To Glycopolymer Base Nanoparticle Gold(I) Conjugate: A New Generation Of Therapeutic Agents
Christian K. Adokoh, James Darkwa, and Ravin Narain
14. Multivalent Glycopolymer-coated Gold Nanoparticles
Sarah-Jane Richards, Caroline I. Biggs, and Matthew I. Gibson
Part III: Surface Immobilized Glycopolymers
15. Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry
Kai Yu, A. Louise Creagh, Charles A. Haynes, Jayachandran N. Kizhakkedathu
16. Oriented Immobilized Sialyloligo-Macroligand Microarray
Satya Nandana Narla and Xue-Long Sun
17. Glycocalyx Remodeling with Glycopolymer-based Proteoglycan Mimetics
Mia L. Huang, Raymond A. A. Smith, Greg W. Trieger, and Kamil Godula
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2015
Pages: 250
Weight: 6542g
Availability: Available
Subcategories: Biochemistry
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